DISSECTING FASXIATOR POTENTIAL AS ALTERNATIVE ANTICOAGULANT BY PREVENTING THROMBOSIS THROUGH INHIBITION OF CONTACT ACTIVATION SYSTEM

Thrombosis, an imbalanced interaction between blood components, contributes greatly to deaths that occur worldwide. Therefore, treatment can reverse the condition of clotting and hypercoagulability is essential. However, drugs used treat thrombosis-based diseases have side effects be seen in short long term, particularly increased risk bleeding. alternative needed overcome problem thrombosis without causing significant endanger lives anticoagulant drug users. The solution this none other than nature provided, a protease inhibitor obtained through venom Bungarus fasciatus snake, Fasxiator.
 Fasxiator dilute inhibition Contact Activation System (CAS) mechanism, specifically inhibiting factor XIa. advantage CAS method it does not affect normal hemostasis, thereby minimizing bleeding problems are common with drugs. Animal studies rats demonstrated properties high target selectivity for XIa, effectiveness, safety profile Fasxiator, enabling application as future.
 based on discussion has been explained above, potential humans future due its selectivity, effectivity, previous animal studies.